PROMOGRAN PRISMA™ Matrix is comprised of a sterile, freeze dried composite of 44% oxidized regenerated cellulose (ORC), 55% collagen and 1% silver-ORC. Silver-ORC contains 25% w/w ionically bound silver, a well-known antimicrobial agent.
Optimum wound environment
PROMOGRAN PRISMA™ Matrix maintains a physiologically moist microenvironment at the wound surface. This environment is conducive to granulation tissue formation, epithelization and optimal wound healing. What is the role of silver in PROMOGRAN PRISMA™ Matrix? The dressing contains ionically bound silver, a well-known antimicrobial agent
How it Works
In the presence of exudate, PROMOGRAN™ PRISMA Matrix transforms into a soft, conformable, biodegradable gel, allowing contact with all areas of the wound.
PROMOGRAN™ PRISMA Matrix maintains a physiologically moist microenvironment at the wound surface. This environment is conducive to granulation tissue formation, epithelialization and optimal wound healing.
What is ORC?
Cellulose is a major component of all plants. Once oxidized, ORC (Oxidized Regenerated Cellulose) is completely bioresorbable, and readily degrades through fluid absorption and subsequent gelling.
Studies show ORC:
• Has hemostatic properties>
• Stimulated cell migration and growth
• Has bactericidal properties
• Reduced protease activity levels, specifically elastase and MMPs
• Scavenged free radicals and bound excess metal ions
Indications and Applications:
PROMOGRAN™ PRISMA Matrix is indicated for the management of wounds healing by secondary intent which are clear of necrotic tissue including:
• Diabetic ulcers
• Venous ulcers
• Pressure ulcers
• Ulcers caused by mixed vascular aetiologies
• Traumatic and surgical wounds
PROMOGRAN PRISMA™ Matrix should be stored away from direct light. Over-exposure to light may cause some discolouration, however this does not affect the release of silver from the dressing. Store below 25 °C / 77 °F. Prepare wound bed per your standard wound care protocol and debride when necessary.
For optimal effect, apply PROMOGRAN PRISMA™ Matrix directly to the whole wound bed.
For a wound with low or no exudate apply PROMOGRAN PRISMA™ Matrix and hydrate with saline or Ringer’s solution. This will initiate the gel forming process.
After hydration the PROMOGRAN PRISMA™ Matrix gel will intimately contact the wound
The biodegradable gel is naturally absorbed over time.
PROMOGRAN PRISMA™ Matrix must be covered with either gauze, a non-adhering or a hydropolymer dressing in order to maintain a moist wound healing environment.
After initial application, re-treat the wound with PROMOGRAN PRISMA™ Matrix up to every 72 hours depending upon the amount of exudate. It is not necessary to remove any residual PROMOGRAN PRISMA™ Matrix. For heavily exuding or infected wounds it may be necessary to retreat the wound with PROMOGRAN PRISMA™ Matrix every 24 hours.
This product is part of 3M’s comprehensive plan for the treatment of diabetic foot ulcers (DFU) and venous leg ulcers (VLU). Biofilm, present in greater than 70% of chronic wounds, causes persistent inflammation and poor wound healing. Wound bed preparation, including the management of biofilm, is an essential element in treating these often-stubborn conditions.